Circulating vaccine-derived poliovirus type 2 (cVDPV2) in Indonesia

On 20 and 27 December 2023, the Indonesian Ministry of Health notified WHO of two confirmed cases of circulating VDPV2. One case, from Klaten district, Central Java province, is a 6-year-old female, with a history of recent travel to Sampang district, East Java province. She developed Acute Flaccid Paralysis (AFP) on 21 November 2023 and had previously received two doses of bivalent oral polio vaccine (bOPV) through routine immunization. The case had not received any dose of inactivated polio vaccine (IPV). The second case is reported from Pamekasan district in East Java province. The case is a one-year-old male with an onset of paralysis on 22 November 2023 with a history of bOPV vaccination (four doses) and one dose of IPV. The sequence result indicates 43 nucleotide changes with the Sabin 2 references.