Repeated vaccinations improve mucous membrane immunity against COVID-19

A recently published study in the journal Science Translational Medicine by researchers from the VIB-UGent Center for Inflammation Research at Ghent University and University Hospital Ghent (Belgium) has demonstrated that repeated vaccinations against SARS-CoV-2 enhance mucous membrane immunity against the virus. The study comprised 183 participants, sampled at multiple points after the administration of primary and booster vaccinations. Individuals who had received multiple doses of mRNA vaccines demonstrated a notable elevation in neutralising antibodies in nasal secretions, which are crucial for impeding the penetration of the airborne SARS-CoV-2 virus. The findings indicate that repeated vaccinations improve the subject’s comprehensive immunity by enhancing the antibody response to the virus and providing a more robust defense against contagion than that of individuals who are unvaccinated or have received previous vaccinations.